Can a PCIe NVME SSD be used in an slot?

NVMe SSDs utilize the NVMe protocol that was specifically designed for SSDs When paired with the PCIe bus, an NVMe SSD offers the latest levels of

ONLY work with NVME or PCIe based drives and not the older SATA based SSD

m2 slot mainboard Faster boots, loads, and saves with 7,4007,000MBs sequential readswrites1 — the Crucial T500 PCle® NVMe® SSD is more than 2x faster6 than Gen3 SSDs and

m2 slot pc SATA is just a complete wasted slot ; all slots should be dual NVMESATA capable, or